Causitive Agent
TB is the world's foremost death from a single infectious agent, caused by mycobacterium tuberculae.
The mycobacteria are slender, rod-shaped, aerobic bacteria that do not form spores. they are similar to other bacterial organisms except for an outer waxy capsule that makes them more resistant to destruction; it can persist in old necrotic and calcified lesions and remain capable of reinitiating growth. The waxy coat also causes the organism to retain red dye when treated with acid that's why it is also called acid-fast bacilli. Although it can infect any organ of the body, the lungs are most frequently involved. The tubercle bacilli are strict aerobic that thrive in any oxygen-rich environment. This explains their tendency to cause disease in the upper lobe or upper parts of the lower lobes of the lung, where ventilation is greatest.
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