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Hydatidiform Mole or Vesicular Mole

Hydatidiform mole (Vesicular Mole)
-it is an abnormal development of placental villi into grapelike cysts filled with viscid material.
  • It is more common for those with Asian heritage, older gravida, and after induction of ovulation with Clomiphene therapy.
  • Uterus is larger than AOG, soft and full lower segment on palpation
  • brown vaginal discharges during 12th week onwards
  •  persistent bleeding

Diagnosis of Hydatidiform (Vesicular) Mole
  •  high HCG level
  • no FHR or palpable fetal parts
  • ultrasound shows no fetal skeleton.
  • increased nausea and vomiting

Management for Hydatidiform (Vesicular) Mole 
  • monitoring and management of shock by blood transfusion or IV therapy
  • mole is removes by vacuum aspiration or curettage
  • educate on avoiding pregnancy for at least one year
  • educate on the need to monitor HCG for 1 year 
  • if there is rise in HCG, further treatment (hysterectomy or chemotherapy) is required

Client needs to have HCG testing every month for a year while using a reliable contraceptive.  
Methotrexate is the drug of choice for prophylaxis.


Ultrasound of Hydatidiform Mole or Vesicular Mole


















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